WE2.10 Regional vessels wrapping following pancreaticoduodenectomy reduce the risk of post-operative extra-luminal bleeding. A systematic review

Abstract Aim Post-pancreatectomy bleeding which may be a potentially fatal complication, usually resulting from the erosion of regional visceral arteries mainly hepatic artery and stump gastro-duodenal artery, caused by leak or fistula pancreatic anastomosis. The objective this article is to assess whether vessels wrapping omentum falciform/teres ligament following pancreaticoduodenectomy reduce risk post-operative extra-luminal bleeding. Method Standard medical electronic databases were searched with help local librarian relevant published randomized controlled trial (RCT) any type comparative trials shortlisted according inclusion criteria. Summated outcome in patients undergoing was evaluated using principles meta-analysis on RevMan 5 statistical software. Result One RCT 6 retrospective 4100 for indication found suitable met-analysis. There 1404 wrap-group (WG) group 2696 no-wrap (NWG). In random effects model analysis, incidence hemorrhage rate statistically lower WG [odd ratio 0.51, 95%, CI (0.31, 0.85), Z=2.59, P=0.01]. moderate heterogeneity between studies; however it not significant. Conclusion (using omentum, falciform ligamentum teres seems However, more RCTs robust quality recruiting higher number are required validate these findings because current study presented combined data one studies.